Form: EFFECT

Notice of Effectiveness

December 10, 2025

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

Notice of Effectiveness

Effectiveness Date: December 10, 2025 5:00 P.M.
Form: S-1
CIK: 0001505497
Company Name: BioRestorative Therapies, Inc.
File Number: 333-291623